name rating rank seed nGene eGene cGene description CYLD 10 1 Y 1 0 9 CYLD lysine 63 deubiquitinase IRF1 9.523418719162054 2 Y 1 0 9 interferon regulatory factor 1 RHOA 8.322701868388258 5 Y 1 0 8 ras homolog family member A ETS2 8.28097906384565 6 Y 0 1 8 ETS proto-oncogene 2, transcription factor IL23R 8.245459364481416 7 Y 1 1 6 interleukin 23 receptor TNFRSF1A 7.788721310908175 9 Y 1 1 6 TNF receptor superfamily member 1A IL10 7.265210410418264 13 Y 1 0 5 interleukin 10 STAT3 7.019404502829437 14 Y 1 1 4 signal transducer and activator of transcription 3 TYK2 6.6319595075847975 20 Y 1 0 7 tyrosine kinase 2 PTPN2 6.50208441497448 23 Y 1 0 6 protein tyrosine phosphatase non-receptor type 2 TNFAIP3 6.477247241687185 24 Y 1 0 6 TNF alpha induced protein 3 IL6R 6.440220935023075 26 Y 1 0 6 interleukin 6 receptor PDGFB 6.369196192094981 30 Y 1 0 5 platelet derived growth factor subunit B IKBKG 6.362445333898351 31 N 0 0 0 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma SMAD3 6.295919296855262 35 Y 1 0 6 SMAD family member 3 TNF 6.2815134628155365 37 N 0 0 0 tumor necrosis factor BIRC3 6.261294899552904 40 N 0 0 0 baculoviral IAP repeat containing 3 IL12RB2 6.244975839561129 42 Y 0 0 4 interleukin 12 receptor subunit beta 2 IL12B 6.235000808614714 43 Y 1 0 4 interleukin 12B STAT1 6.205401685043944 44 N 0 0 0 signal transducer and activator of transcription 1 NFKB1 6.186874357109224 45 Y 1 0 1 nuclear factor kappa B subunit 1 NFKBIA 6.182560197984067 46 Y 0 0 6 NFKB inhibitor alpha ERBB2 6.111300225819198 54 Y 0 0 5 erb-b2 receptor tyrosine kinase 2 BIRC2 6.0743400940531975 58 N 0 0 0 baculoviral IAP repeat containing 2 TAB3 6.0157676556332635 60 N 0 0 0 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 JUN 6.015374942330359 61 N 0 0 0 Jun proto-oncogene, AP-1 transcription factor subunit IKBKB 5.9959795231696145 62 N 0 0 0 inhibitor of nuclear factor kappa B kinase subunit beta TRAF2 5.97438345048485 63 N 0 0 0 TNF receptor associated factor 2 CD40 5.952987377097113 64 Y 1 0 7 CD40 molecule CHUK 5.940569146888616 66 N 0 0 0 component of inhibitor of nuclear factor kappa B kinase complex TRAF6 5.939206199133509 67 N 0 0 0 TNF receptor associated factor 6 STAT4 5.9377474939418775 68 N 0 0 0 signal transducer and activator of transcription 4 RELA 5.88092784741756 73 Y 0 0 2 RELA proto-oncogene, NF-kB subunit IL2RA 5.878394049628821 74 Y 1 0 4 interleukin 2 receptor subunit alpha IFNG 5.863748289870955 75 Y 0 0 1 interferon gamma ETS1 5.826722226578294 77 Y 1 0 3 ETS proto-oncogene 1, transcription factor JAK1 5.806161870567351 79 N 0 0 0 Janus kinase 1 TAB1 5.7800711777967475 83 N 0 0 0 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TAB2 5.772261239688702 84 N 0 0 0 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 FOS 5.759848441204069 85 Y 1 0 2 Fos proto-oncogene, AP-1 transcription factor subunit JAK2 5.759755529299205 86 Y 1 0 0 Janus kinase 2 TRADD 5.7286126812810885 92 N 0 0 0 TNFRSF1A associated via death domain RIPK1 5.7221947690516295 94 N 0 0 0 receptor interacting serine/threonine kinase 1 FADD 5.718263745940793 96 N 0 0 0 Fas associated via death domain IL2 5.713717873649072 97 Y 1 0 1 interleukin 2 LTBR 5.704903771540606 99 Y 1 1 5 lymphotoxin beta receptor XIAP 5.679968700290862 101 N 0 0 0 X-linked inhibitor of apoptosis TRAF3 5.6640708476957515 106 N 0 0 0 TNF receptor associated factor 3 STAT6 5.6607193249379355 107 N 0 0 0 signal transducer and activator of transcription 6 MAP3K7 5.65486022262673 109 Y 0 0 1 mitogen-activated protein kinase kinase kinase 7 TLR4 5.649217715370713 111 Y 1 0 5 toll like receptor 4 PIK3R1 5.648477444995659 112 N 0 0 0 phosphoinositide-3-kinase regulatory subunit 1 IFNB1 5.640289876667655 113 N 0 0 0 interferon beta 1 IL13 5.6273886801645885 115 Y 0 0 1 interleukin 13 IL19 5.623607522135121 117 Y 1 0 2 interleukin 19 SOCS1 5.591925732100427 120 Y 1 0 3 suppressor of cytokine signaling 1 RIPK3 5.563892287410602 123 N 0 0 0 receptor interacting serine/threonine kinase 3 IL4 5.501452848377775 129 N 0 0 0 interleukin 4 MAPK3 5.377620576556079 152 N 0 0 0 mitogen-activated protein kinase 3 MAPK8 5.347980015169985 158 N 0 0 0 mitogen-activated protein kinase 8 FOXO3 3.824075522310733 811 N 0 0 0 forkhead box O3